Amlodipine is a long acting dihydropyridine calcium channel blocker prescribed for hypertension and the management of chronic stable angina. It functions by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle cells, leading to systemic vasodilation and decreased peripheral resistance. One of the classic side effects associated with peripheral vasodilation is peripheral edema, presenting as swelling in the lower extremities. Patients should monitor for this effect and discuss management options with their provider rather than discontinuing therapy. Unlike shorter acting agents, its gradual onset of action minimizes the risk of acute reflex tachycardia, making it a stable choice for cardiovascular maintenance.